Search submitted abstracts

1

Characterising a novel tumour suppressor in liver cancer

Abu Zaid Khan

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Characterising a novel tumour suppressor in liver cancer

2

Novel HIF-2α Phosphorylation Abolishes Transcriptional Activity By Preventing Heterodimerisation with HIF-1β.

Adam Albanese

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Novel HIF-2α Phosphorylation Abolishes Transcriptional Activity By Preventing Heterodimerisation with HIF-1β.

3

Oxygen metabolism controls call fate specification and morphogenesis in in vitro mouse embryo models

Alba Villaronga Luque

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Oxygen metabolism controls call fate specification and morphogenesis in in vitro mouse embryo models

4

Tumor adaptation to hyperoxic and PARP inhibitors treatment.

Ana Belén Herrera Campos

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Tumor adaptation to hyperoxic and PARP inhibitors treatment.

5

Endothelial HIF2a Signalling Modulates Hypoxia Driven Myeloid Cell Migration into the Lung

Andrew Cowburn

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Endothelial HIF2a Signalling Modulates Hypoxia Driven Myeloid Cell Migration into the Lung

6

Nuclear actin shaping the transcriptional response to hypoxia parallel to the HIF pathway

Anika Göpel

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Nuclear actin shaping the transcriptional response to hypoxia parallel to the HIF pathway

7

Targeting oxygen distribution in the fracture gap to induce vascularized bone healing

Annemarie Lang

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Targeting oxygen distribution in the fracture gap to induce vascularized bone healing

8

The mitochondrial Na+/Ca2+ exchanger NCLX is implied in the activation of hypoxia-inducible factors: a link between acute and HIF-mediated hypoxia responses?

Antonio Martínez-Ruiz

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The mitochondrial Na+/Ca2+ exchanger NCLX is implied in the activation of hypoxia-inducible factors: a link between acute and HIF-mediated hypoxia responses?

9

Bioreductive fluorescent probes to image different levels of hypoxia in human and plants

Antoine L. D. Wallabregue

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Bioreductive fluorescent probes to image different levels of hypoxia in human and plants

10

Measurements of pO2 in Zebrafish Embryos

Artem Govorukhin

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Measurements of pO2 in Zebrafish Embryos

11

Characterization of the roles of HIF-P4H-2, HIF1α and HIF2α in ECM signalling

Atte Tapiola

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Characterization of the roles of HIF-P4H-2, HIF1α and HIF2α in ECM signalling

12

Inhibition of microRNA-34a signaling impairs hypoxia responses in diabetic wounds through metabolic reprogramming and macrophage polarization

Bo Yan

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Inhibition of microRNA-34a signaling impairs hypoxia responses in diabetic wounds through metabolic reprogramming and macrophage polarization

13

The transcriptional changes in neuroblastoma cellular hypoxia response: a core neuroblastoma hypoxia signature

Chun-Sui Kwok

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The transcriptional changes in neuroblastoma cellular hypoxia response: a core neuroblastoma hypoxia signature

14

Microtubule disruption abrogates hypoxia-induced upregulation of glycolysis

Darragh Flood

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Microtubule disruption abrogates hypoxia-induced upregulation of glycolysis

15

Carotid body vascularization relies on O2-sensing cells-derived VEGFA.

David Macias Gutierrez

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Carotid body vascularization relies on O2-sensing cells-derived VEGFA.

16

Quantitative metabolic imaging of tissue O2 and pH in animal models of hypoxia

Dmitri Papkovsky

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Quantitative metabolic imaging of tissue O2 and pH in animal models of hypoxia

17

Purinergic signaling in renal fibrosis

Dr. Anna-Lena Forst

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Purinergic signaling in renal fibrosis

18

Hypoxia and HIF-1 upregulate the expression of the glycerophospholipid and triacyglyceride synthesis enzyme AGPAT4.

Effrosyni Paraskeva

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Hypoxia and HIF-1 upregulate the expression of the glycerophospholipid and triacyglyceride synthesis enzyme AGPAT4.

20

Maturation of the Carotid Body Transcriptome in Fetal and Postnatal Life

Emma Jane Hodson

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Maturation of the Carotid Body Transcriptome in Fetal and Postnatal Life

21

The effect of CO-releasing molecules on the activation of the hypoxia response

Emma Klemola

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The effect of CO-releasing molecules on the activation of the hypoxia response

22

Precise electrical manipulation of oxygen and reactive oxygen species gradients in biological environment

Eric Glowacki

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Precise electrical manipulation of oxygen and reactive oxygen species gradients in biological environment

23

Tankyrases regulate anaerobic glycolysis through HIF-1α disabling

Esteban Zamudio Martínez

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Tankyrases regulate anaerobic glycolysis through HIF-1α disabling

24

Biochemical and structural investigations of putative pseudomonal prolyl 4 hydroxylase involved in the resistance to siderophore conjugated antibiotics

Faisal M Alshref

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Biochemical and structural investigations of putative pseudomonal prolyl 4 hydroxylase involved in the resistance to siderophore conjugated antibiotics

25

Underlying influences on the distribution pattern of renal EPO+ cells

Firmke Bettina

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Underlying influences on the distribution pattern of renal EPO+ cells

26

Phosphorylation by CK1δ mediates the association of HIF-1α with microtubules and its symmetrical distribution to daughter cell nuclei after mitosis.

George Simos

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Phosphorylation by CK1δ mediates the association of HIF-1α with microtubules and its symmetrical distribution to daughter cell nuclei after mitosis.

27

Short chain fatty acids as key mediators in counteracting hypoxia dependent stress in neuronal cells

Francesco Maria Grasselli

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Short chain fatty acids as key mediators in counteracting hypoxia dependent stress in neuronal cells

28

Hypoxia-inducible miR-155 dysregulates epithelial barrier by attenuating claudin-7 in eosinophilic esophagitis

Gary Markey

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Hypoxia-inducible miR-155 dysregulates epithelial barrier by attenuating claudin-7 in eosinophilic esophagitis

30

Interplay of hypoxia signaling and kynurenine pathway in PPGLs

Gintare Zygiene

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Interplay of hypoxia signaling and kynurenine pathway in PPGLs

31

Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy

Gregory Wyant

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Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy

32

SINHCAF: a novel regulator of HIF signalling

Harry Collier

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SINHCAF: a novel regulator of HIF signalling

33

Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase

Hudson Coates

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Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase

34

Maximal myocardial blood flow and minimal vascular resistance in untrained and endurance-trained men

Ilkka Heinonen

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Maximal myocardial blood flow and minimal vascular resistance in untrained and endurance-trained men

35

HIF signalling enhances innate immune control of Pneumovirus Replication

Jane McKeating

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HIF signalling enhances innate immune control of Pneumovirus Replication

36

Exploring Specificity in KDM5 Structurally Conserved Histone Demethylase Paralogs with Oxygen-Sensing Chromatin Remodeling Functions

Jiahua Kou

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Exploring Specificity in KDM5 Structurally Conserved Histone Demethylase Paralogs with Oxygen-Sensing Chromatin Remodeling Functions

37

Oxygen Sensing and Placental Cell Differentiation

Johanna Lattner

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Oxygen Sensing and Placental Cell Differentiation

38

The myeloid-related loss of hypoxia-inducible factors promotes the tumor initiation and metastasis in a spontaneous breast cancer model

Johanna Tiebel

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The myeloid-related loss of hypoxia-inducible factors promotes the tumor initiation and metastasis in a spontaneous breast cancer model

39

Elevated Hemoglobin of Andean Aymaras is Caused by Alternatively Spliced NFKB1

Josef Prchal

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Elevated Hemoglobin of Andean Aymaras is Caused by Alternatively Spliced NFKB1

40

UNANTICIPATED ROLE OF HIF1Α IN TUMOR CELL GLUCOSE METABOLISM

Julián Aragonés López

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UNANTICIPATED ROLE OF HIF1Α IN TUMOR CELL GLUCOSE METABOLISM

41

Hypoxic response and directed migration towards oxygen in amoebae

Julie HESNARD

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Hypoxic response and directed migration towards oxygen in amoebae

42

Post-translational modifications in antimicrobial resistance

Karina Alexandra Calvopina Tapia

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Post-translational modifications in antimicrobial resistance

43

Hypoxia promotes a detrimental neutrophil phenotype with increased capacity for tissue damage in ANCA-associated vasculitis

Katharine Lodge

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Hypoxia promotes a detrimental neutrophil phenotype with increased capacity for tissue damage in ANCA-associated vasculitis

44

Hypoxia-Inducible Factor-1 activated by PIM1 assembles a non-canonical transcription complex and resultant regulon that drives progression of JAK2V617F myeloproliferative neoplasms

Katherine Bridge

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Hypoxia-Inducible Factor-1 activated by PIM1 assembles a non-canonical transcription complex and resultant regulon that drives progression of JAK2V617F myeloproliferative neoplasms

45

THE ADAPTATION OF THP-1 CELLS TO HYPOBARIC HYPOXIA DIFFERS FROM THAT TO NORMOBARIC HYPOXIA

Katrin Stein

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THE ADAPTATION OF THP-1 CELLS TO HYPOBARIC HYPOXIA DIFFERS FROM THAT TO NORMOBARIC HYPOXIA

46

Activation of Epo-producing cells by HIF stabilizers in the kidney and beyond

Knöpfel Thomas

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Activation of Epo-producing cells by HIF stabilizers in the kidney and beyond

47

Activation of rat carotid body neurogenic niche by chronic intermittent hypoxia

Lin Gao

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Activation of rat carotid body neurogenic niche by chronic intermittent hypoxia

48

The Role of HIF Regulatory Pathways in CD8+ T Cell Metabolism

Madara Brice

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The Role of HIF Regulatory Pathways in CD8+ T Cell Metabolism

49

Divergent Effects of Hypoxia on Polyamine Metabolism

Maider Fagoaga-Eugui

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Divergent Effects of Hypoxia on Polyamine Metabolism

50

Boosting Oxygen Diffusion in the Radioresistant Oesophageal Tumour Microenvironment to Improve Radiotherapy

Maitiú Ó Murchú

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Boosting Oxygen Diffusion in the Radioresistant Oesophageal Tumour Microenvironment to Improve Radiotherapy

51

Single-cell variability of hypoxia-inducible gene expression

Malgorzata Wilk

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Single-cell variability of hypoxia-inducible gene expression

52

DOES TRANSCRIPTIONAL CYCLIN-DEPENDENT KINASE SIGNALLING PLAY A CAUSATIVE ROLE IN PULMONARY HYPERTENSION?

Manpreet Kaur

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DOES TRANSCRIPTIONAL CYCLIN-DEPENDENT KINASE SIGNALLING PLAY A CAUSATIVE ROLE IN PULMONARY HYPERTENSION?

53

Smoking and Hypoxia: Contribution to vascular dysfunction in chronic obstructive pulmonary disease

MARÍA CALZADA

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Smoking and Hypoxia: Contribution to vascular dysfunction in chronic obstructive pulmonary disease

54

Investigating the interplay between the TNF superfamily factor 14/LIGHT and HIF in inflammatory fibroblasts

Mario Manresa

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Investigating the interplay between the TNF superfamily factor 14/LIGHT and HIF in inflammatory fibroblasts

55

Characterization of 3D human pulmonary epithelial models under inflammatory hypoxia

Maura Lynch-Miller

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Characterization of 3D human pulmonary epithelial models under inflammatory hypoxia

56

Hypoxia triggers dermal fibrogenesis by activating intracellular and extracellular collagen maturation processes

Méline RICOL

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Hypoxia triggers dermal fibrogenesis by activating intracellular and extracellular collagen maturation processes

57

Glucocorticoids regulate the expression of HIF-3a through GR

Meina Zhang

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Glucocorticoids regulate the expression of HIF-3a through GR

58

HIF prolyl 4-hydroxylase-2 is a novel target for retinopathy of prematurity

Mikko Karpale

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HIF prolyl 4-hydroxylase-2 is a novel target for retinopathy of prematurity

59

Humanized monoclonal antibodies specific for CA IX protein are able to suppress hypoxia

Monika Barathova

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Humanized monoclonal antibodies specific for CA IX protein are able to suppress hypoxia

60

Chronic lung disease and hypoxia-induced changes in the brain microenvironment: implications in pre-metastatic niche formation

Nazli Salik

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Chronic lung disease and hypoxia-induced changes in the brain microenvironment: implications in pre-metastatic niche formation

61

The molecular identity of erythropoietin-producing cells in healthy, fibrotic and PHI-treated mice

Olga Lempke

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The molecular identity of erythropoietin-producing cells in healthy, fibrotic and PHI-treated mice

62

Visualising the Interplay Between Coronavirus replication and the Cellular Hypoxic Response

Peter Wing

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Visualising the Interplay Between Coronavirus replication and the Cellular Hypoxic Response

63

The oxygen-sensing pathway in neural cells controls intrinsic long-term neuroregeneration after ischemic stroke

Pinar Khalili

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The oxygen-sensing pathway in neural cells controls intrinsic long-term neuroregeneration after ischemic stroke

64

Hypoxia-inducible pathway mitigates mitochondrial dysfunction in pancreatic beta cells

Raphael Fagundes Rosa

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Hypoxia-inducible pathway mitigates mitochondrial dysfunction in pancreatic beta cells

65

A role of EZH2-dependent regulation of HIF2α in the chronic hypoxia response in cancer

Salisa Kruijning

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A role of EZH2-dependent regulation of HIF2α in the chronic hypoxia response in cancer

66

The impact of oxygen tension on neutrophil biomechanical profiles in Pulmonary Arterial Hypertension

Sara Nakanishi

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The impact of oxygen tension on neutrophil biomechanical profiles in Pulmonary Arterial Hypertension

67

Hypoxia reinforces tumour microevolution and therapy resistance by promoting CA9-mediated formation of cell-in-cell structures

Silvia Pastorekova

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Hypoxia reinforces tumour microevolution and therapy resistance by promoting CA9-mediated formation of cell-in-cell structures

68

HIF signaling control is essential for postnatal cardiomyocyte maturation and cardiac function

Sonia Urra Balduz

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HIF signaling control is essential for postnatal cardiomyocyte maturation and cardiac function

69

CHARACTERIZING THE HYPOXIC THRESHOLD OF PULMONARY MICROVASCULAR ENDOTHELIAL CELLS

Sonja Hersel

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CHARACTERIZING THE HYPOXIC THRESHOLD OF PULMONARY MICROVASCULAR ENDOTHELIAL CELLS

70

The Prognostic Significance of the Spatial Distribution of Tumor Associated Macrophages in Colorectal Cancer

Sophia Holten

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The Prognostic Significance of the Spatial Distribution of Tumor Associated Macrophages in Colorectal Cancer

70

Activation of the hypoxia-inducible factor (HIF) pathway by roxadustat improves glucose metabolism in human primary myotubes

Tuulia Ala-Nisula

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Activation of the hypoxia-inducible factor (HIF) pathway by roxadustat improves glucose metabolism in human primary myotubes

71

Real-time monitoring of single-cell heterogeneity in HIF dependent gene transcription

Stana Martina Burger

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Real-time monitoring of single-cell heterogeneity in HIF dependent gene transcription

72

HIF1α Induction of MicroRNA Expression in the Regulation of Steroidogenesis Under Acute Hypoxic Stress in vitro and in vivo

Stephen Ariyeloye

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HIF1α Induction of MicroRNA Expression in the Regulation of Steroidogenesis Under Acute Hypoxic Stress in vitro and in vivo

73

HUMAN PRIMARY ENDOTHELIAL CELLS EXPRESS FACTORS INVOLVED IN PROLIFERATION OF ADULT CARDIOMYOCYTES UNDER MODERATE HYPOXIC CONDITIONS

Stilla Frede

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HUMAN PRIMARY ENDOTHELIAL CELLS EXPRESS FACTORS INVOLVED IN PROLIFERATION OF ADULT CARDIOMYOCYTES UNDER MODERATE HYPOXIC CONDITIONS

74

Deubiquitinating enzyme mutagenesis screens identify a USP43 driven HIF-1 transcriptional response

Tekle Pauzaite

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Deubiquitinating enzyme mutagenesis screens identify a USP43 driven HIF-1 transcriptional response

75

Identification of the proper subset responsible for erythropoietin production among renal fibroblasts

Taku Nakai

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Identification of the proper subset responsible for erythropoietin production among renal fibroblasts

76

Genetic and pharmacological inhibition of pyruvate dehydrogenase kinases (PDKs) enhance chemotoxicity in gastric cancer cells

Thomas Schaschinger

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Genetic and pharmacological inhibition of pyruvate dehydrogenase kinases (PDKs) enhance chemotoxicity in gastric cancer cells

77

Regulation of the Cellular Response to Hypoxia by N6-methyladenosine

THEODORA SIDERI

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Regulation of the Cellular Response to Hypoxia by N6-methyladenosine

78

SARS-CoV-2 induces vital NET formation independent of available oxygen

Timo Henneck, PhD

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SARS-CoV-2 induces vital NET formation independent of available oxygen

80

The role of the lysine-specific histone demethylase 5B (KDM5B) in epigenetic regulation in renal tubular cells

Victoria Lauer

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The role of the lysine-specific histone demethylase 5B (KDM5B) in epigenetic regulation in renal tubular cells

81

Impaired adaptive responses to hypoxia in patients with diabetes

Xiaowei Zheng

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Impaired adaptive responses to hypoxia in patients with diabetes

82

Crosstalk between the Hippo pathway coactivator Yes-Associated Protein and NADPH oxidases promotes the cardiac response to hypoxia

Xinpei Chen

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Crosstalk between the Hippo pathway coactivator Yes-Associated Protein and NADPH oxidases promotes the cardiac response to hypoxia

83

Evaluation of the ability of an oxygen carrier to increase radiosensitivity in a BxPC3 model under normoxic/hypoxic conditions

Xuehua Lin

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Evaluation of the ability of an oxygen carrier to increase radiosensitivity in a BxPC3 model under normoxic/hypoxic conditions

84

KINETIC STUDIES ON HUMAN JUMONJI-C HYDROXYLASE JMJD7

Yicheng Wang

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KINETIC STUDIES ON HUMAN JUMONJI-C HYDROXYLASE JMJD7

85

Hypoxia signaling and histone deacetylases govern developmental stage-specific erythropoietin production in embryonic neural cells

Yuma Iwamura

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Hypoxia signaling and histone deacetylases govern developmental stage-specific erythropoietin production in embryonic neural cells

87

Multimodal Stimulation and Measurement Platform for Micro-Engineering Heart Tissues (μEHTs)

Joose Kreutzer

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Multimodal Stimulation and Measurement Platform for Micro-Engineering Heart Tissues (μEHTs)

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